1. How are drugs sorted into therapeutic groups and classes?
3. What does AMA stand for?
A. American Medical Academy
B. American Medical Accreditation
C. American Medical Association
D. Association of Medical Assistants
4. What section of a drug's package insert describes situations in which the drug should not be used because the risks outweigh the therapeutic benefits?
A. adverse reactions
5 What is tertiary care?
A. adding medications together to achieve a better clinical effect
B.highly specialized medical and surgical care provided by a large medical center for unusual or complex medical problems
C. receiving medical or surgical care that does not require an overnight stay in the treatment facility
D. seeing a physician for routine checkups and general healthcare
6. Which of the following is NOT one of the stages in the classic approach to brand development strategy covered in your manual?
A. brand personality
B. brand positoning
D. brand values
7 What are vasodilators used to do?
A. decrease vascular resistance and increase blood flow
B. mimic pathogens to stimulate the immune system
C. narrow the blood vessels
D.stimulate the CNS to make the heart beat faster
8. What is the name of the condition that occurs after a specific dose of a drug is given at such regular intervals that absorption and elimination (and therefore drug plasma concentration) have become fairly constant?
9. Which statement is TRUE about ocular administration?
10. Which entities invest's the most money in pharmaceutical R&D?
A. Canadian pharmaceutical companies
B. the NIH
11. How are most drugs excreted?
A. via the bloodstream
B. via the heart
C. via the kidneys
D. via the skin
12. Over the last few decades, what has happened to legal limitations on sales' reps discussions about off label uses?
13. Answer: Branding name
14. What does it mean if two drugs are at parity?
15 Who is most likely to benefit from electronic sampling programs?
A. Everyone would benefit equally from electronic sampling programs
B. physicians in hospitals who are too busy to see representatives
C. physicians in rural areas who are not as frequently visited by representatives
D. physicians in urban areas who are too busy to see representatives
16. When referring to medication dosage, which abbreviation means "one-half':
17 What is an internist?
A. a physician who practices internal medicine
B. a physician's intern
C. a type of oncologist who specializes in chemotherapy
D. an internal sales representative
18. Which of the following is a type of white blood cell?
19. Why are novice sales representatives often placed in charge of negotiating MCO formularies?
A. to become more familiar with the healthcare industry
B. to become more familiar with their territories
20. What distinguishes pharmacodynamics from pharmacokinetics?
21 What proportion of the drugs tested on human subjects are eventually approved by the FDA?
A. about 20%
B. about 60%
C. about 70%
D. about 95%
22. According to a study discussed in your manual, how do most physicians prefer to receive their drug samples?
A. by borrowing them from hospitals
B. by ordering them over the Internet
C. by trading them for services
D.directly from sales representatives
23. Which of the following is an example of a central value?
24. Which of the following specialties likely has the MOST emergency calls?
25. What affects the rate of active transport?
C. the availability of carriers and energy
D. neither the availability of carriers nor the availability of energy
26. Over the last few decades, what has happened to the FDA approval time for new drugs?
B. It has been lengthened to limit DTC marketing
C. It has been shortened to improve drug quality
27. Which of the following would NOT help improve compliance?
A. patients liking their providers
B. patients using only one pharmacist
C. pharmacists understanding how generics differ from brand name drugs
D. support groups
28. Which entity chooses a drug's trade name?
A. the drug's inventor
B. the drug's manufacturer
D. the United States Pharmaceutical Council
29. What type of stem cells are obtained from embryos and can develop into any cell type?
30. As the price a patient pays for a prescription increases, what happens to the likelihood that the patient will fill it?
31. Most involuntary movements come from which type of muscle tissue?
A. cardiac and smooth
B. only skeletal
C. skeletal and cardiac
D. skeletal and smooth
32. Which of the following is NOT one of the body's major organ systems?
A. the cardiovascular system
B. the cellular system
C. the gastrointestinal system
D. the musculoskeletal system
33. How do most drugs exert their primary physiological effects?
A. by activating synapses between different types of tissues
B. by binding to cell receptors that are sensitive to their presence
C. by inhibiting synapses between different types of tissues
D. through genetic mutation
34. What is the most reliable source of information for determining therapeutically equivalent drug products?
A. AMA guide
B. Blue Book
C. FDA drug list
D. Orange Book
35. What does subcutaneous mean?
A. beneath the intervention
B. beneath the muscle tissue
C. beneath the outer skin
D. beneath the suture
36. What should a sales representative do if all of the prime spaces in a drug cabinet are coccupied?
A. ask staff for permission to move some of the other products in the cabinet
B. ask staff for permission to throw away expired products in the cabinet
C. ask the doctor if he still needs some of the other products in the cabinet
D. surreptitiously move your largest competitors' products out of the way
37. It is inappropriate for physicians' prescribing behaviors to be educated by their personal tastes and idiosyncrasies
39. What are the 2 legal classifications of wholesalers?
A. distributors and supply chains
B. pharmacists and NAMs
C. primary and secondary wholesale distributors
D. retailers and institutions
40.What term describes the usage of a medication for purposes other than the FDA-approved indications on the labeling?
A. contraindicative indication
B. off-indication usage
C or D. off-label
41. What is the acronym for pharmacokinetics?
43. What is typically NOT a characteristic of a pharmaceutical sales rep?
44. What entity grants drug patents?
A. the FDA
45. Which of the following refers to all active and inert pharmaceutical ingredients in a drug, including fillers and colors?
46. What is the difference between potency and efficacy?
47. What is the minimum level of education required for a nurse practitioner?
A. a certification program
B. an associate's degree
C. a bachelor's degree
D. a graduate degree
48. How many names must a drug have?
A. at most three
B. at least three
C. at most five
D. at least five
49. How has a longer development time increased the cost of bringing a new drug to market?
Answer: Increasing the cost of capital
Explaination (Option Not taken so find out in below para): Lengthening development time dramatically increase the cost of bringing a new drug to market by increasing the cost of capital needed for R&D. The cost of capital increases as companies are exposed to Economic Risk and uncertainty over a longer period of development time. Stringent FDA guideline and long approval times have greatly increased the cost of developing new drugs.
51. What agency regulates the distribution and use of narcotics?
52. What is passive diffusion?
A. a type of pinocytosis
B. membrane transport via vesicles
C. the use of energy to help a substance pass from a low concentration gradient to a high one
D. when a substance freely moves through a membrane from a high concentration gradient to a low one
53. What are the MAIN categories of drugs under FDA jurisdiction?
A. active drugs and active placebos
B. biopharmaceuticals and nutraceuticals
C. non-prescription and nutraceuticals
D. prescription and non prescription
54. Answer: Oxytocin
55. What are all metabolites?
A. active substances
B. inactive substances
D. products of metabolism
56. When a drug is administered orally, where does first-pass metabolism occur?
57. What is the medical term for swelling?
58. Which of the following is NOT part of the Seven Step Cascade of Emotion?
B. identify what your product does
D. visualize the power of 10
59. Which part of a clinical research paper is frequently referred to as the road map?
C. letter to the editor
D . methods
60. Which of the following is a main active ingredient in lung surfactants?
A. animal lung extract
C. sympathomimetic drugs
61. What does parenteral mean?
A. child prescriptions
62. Which term denotes a type of substance that enhances the action of a drug or antigen?
63. If a sales representative's product is placed on the second tier of a standard three-tier formulary, which of the following is most likely true?
64. Which of the following is NOT one of the four basic transport mechanisms?
A. active transport
C. passive diffusion
65. Which statement accurately describes a relationship between drug agonists and antagonists?
66. What is the study of the effects and movement of drugs in the human body?
C. clinical pharmacology
67. According to your manual, what is a common complaint that physicians have about traditional sampling methods?
A. that drug sample supply is too unpredictable
B. that patients are less likely to take free samples because they think they are lower quality
C. that patients do not like seeing drug representatives in their offices
D. that they receive too many drug samples
68. Which of these entities is formed by two or more hospitals or other healthcare entities to negotiate reduced rates with its aggregated purchasing power?
B. In-state wholesaler
69. What is another name for a drug derived from a biologic compound?
A. large molecule
D. small molecule
70. What is the most common policy regarding pharmaceutical reps dispensing drug samples in hospitals?
71 Which of the following would help you build trust with a physician?
A. asking if he or she is having any problems with the managed care coverage of your products
B. repeating a question you already asked
C. surprising the office staff with a new poster in the break room
72. What term denotes the difference between the usual effective dose and the dose that induces severe or life-threatening side effects?
A. dose-response relationship
B. margin of safety
C. the placebo effect
D. therapeutic window
73. What are excipients?
A. a type of cell receptor to which antagonists bind to decrease the effects of the body's natural agonists
B. another term for generic equivalents
C. sites of action besides the target sites of action
D. the inert ingredients in a drug formulation
74. What is another term for the AWP?
A. dock-to-dock price
B. float price
C. list price
D. non-stock price
75. Which of these is the most likely use for a uterotonic agent?
A. to induce labor
B. to make the urine more alkaline
C. to supplement oral food intake
D. to treat hyperthyroidism
76. As of November 2013, which of these countries has legalized DTC advertising of prescription drugs?
D. none of these
77. Why are oral drugs often taken on an empty stomach?
A. to be more wholly absorbed by the stomach
B. to minimize absorption by the intestine
C. to minimize nausea
D.to pass through the stomach more quickly
78. What is one factor that differentiates community health centers from hospitals?
D. None of these
79. How does drug sampling provide a social benefit?
80. Which medical term denotes the use of a stethoscope to listen to the heart?
81. What do enteric coatings do?
A. facilitate vomiting
B. help drugs dissolve in the stomach
C. help drugs enter the bloodstream more quickly
D. prevent dissolution in the stomach
82. What is the duration of exclusivity for orphan drugs?
A. 6 months
B. 1 year
C. 7 years
D. 15 years
83. What do National Account Managers do?
A. act as the sales reps' primary point of contact with the rest of the corporation
B. manage the FDA approval process
C. negotiate contracts with MCOs and PBMs
D. sell only to pharmacies
84. What does it usually mean if a drug recall is voluntary?
85. Which phase of clinical trials is also known as the pivotal phase?
A. Phase I
B. Phase III
C Phase IV
D. Phase IX
86. During which phase of clinical trials is the new drug's safety and effectiveness first tested in the target group?
B. Phase I
C. Phase II
D. Phase III
87. How do antacids work?
A. by increasing blood flow to the stomach
B. by lowering gastric pH
C. by raising gastric pH
D. by suppressing cholesterol formation by the liver
88. What is one of the biggest time wasters for a pharmaceutical sales rep?
D. travel time
89. What happens when equilibrium is reached?
A. equal numbers of molecules cross the membrane in both directions
B. molecules stop moving
C. the concentration gradient decreases indefinitely
D. the concentration gradient increases indefinitely
90. What are the most common vectors used in gene therapy?
A. autologous antigens
C. naked DNA
91. What is the percentage fee that the dispenser pays the wholesaler for distribution?
A. margin fee
C. standard fee
92. What is the difference between a chronic (or continuing) reaction, and a delayed reaction?
93 What is clinical effect?
A. federally funded research condition
B. the effect of maximum dosage
C. the response produced by a medication
D. the use of treatment drugs in chemotherapy
94. Which of the following is an example of noncompliance?
A. a patient forgetting to take a drug at a specified time of day
C. a pharmacist dispensing a generic equivalent of a drug instead of the brand name
D. a physician refusing to prescribe a drug because he or she does not trust the clinical studies on it
95. What is the average circulation time of blood?
A. about a minute
B. about 5 minutes
C. about 5 to 10 minutes depending on the patient's age and health conditions
D. about 10 minutes
96. What is one way in which pharmaceutical selling is different from selling in most other industries?
97. From what types of entities do primary wholesale distributors buy most of their drugs?
B. buying clubs
98.What is the Office of the Inspector General (01G)?
A. a department in pharmaceutical companies
B. an arm of the Department of Health and Human Services
C. an arm of the European Medicines Agency D an arm of the FDA
99. What are doctors required to consider when deciding whether or not to prescribe a particular drug?
A. quantity of life over quality of life
B. that no drugs with adverse effects should ever be used
C. the inferiority of OTC drugs
D. the severity of the disorder being treated and the effect it has on the patient's quality of life
100. Which entity assigns a new drug its generic names?
A. the drug's inventor
B. the Food and Drug Administration
C. the United States Adopted Name Council
D. the United States Pharmaceutical Council
D. none of these
102. What is necessary for a drug to be excreted extensively via the kidneys?
103. Which organization or individual initiates the clinical trial and finances the study?
A. clinical research organization
105. Under PhRMA Code, is it acceptable or unacceptable for a pharmaceutical sales rep to take a physician and the physician's spouse to a fundraising dinner?
A. acceptable if only the physician attends
C. acceptable if the total is under $100
107. What term denotes the the extent, quality, or degree to which a substance is poisonous or harmful to the body?
108. What issue has MOST encouraged consumers' desire to see more OTC medications?
A. a weaker patients' rights movement
B.lack of insurance coverage
C. less reliance on the Internet
D. proliferation of herbal remedies
109. What is the degree to which a medication produces a therapeutic effect?
110. What is the most important benefit of electronic prescribing?
111. When does the FDA regulate generic drugs?
A. only if they are branded generics
B. only if they have been contested
112. Which phase of trials largely determines the clinical dose?
A. preclinical trials
B. Phase II trials
C. Phase III trials
D. Phase IV trials
113. What is an advantage of inactivated vaccines over attenuated vaccines?
114. Which medical term denotes a low supply of oxygen due to low blood flow?
115. What are the two main types of prescription drug marketing?
116. What is the site of delivery for subcutaneous injections?
A. fatty tissuebeneath the surface of the skin
B. lymphatic tissue
C. muscle tissue
D. the stomach, via a special type of needle
117. What must be contained in the Description section of a pharmaceutical package insert?
A. adverse effects
B. mechanism of action
D. the proprietary name and the established name
118. What is the study of a medication's effects as it travels through the body?
A. closing of the sale
B. first time advantage
C. likeability factor
D. power of knowledge
120. What is penicillin's primary mechanism of action?
B It inhibits the production of viruses.
D. It sends a messenger to the bone marrow to produce extra white blood cells
122. How does pharmaceutical marketing help narrow the treatment gap?
D. all of these
123. What do immunosuppressive agents do?
A. decrease risk of infection
B. increase risk of infection
C. reduce the risk of rejection of foreign bodies
D. treat psoriasis
124. What types of drugs are EGFR inhibitors?
B. cardiovascular agents
C. CNS agents
D. mitotic inhibitors
125. Which of the following means outside of the living body?
A. en vivo
B. ex vitro
C. ex vivo
D. intra vivo
A. $5-10 billion
B. $40-50 billion
C. $800-900 billion
D.$ 2-5 trillion
128. Which statement is TRUE regarding post-approval drug monitoring?
129. Which term denotes when tolerance to one medication causes increased tolerance to another medication?
A. cell tolerance
C. indicated tolerance
D. minimized tolerance
131. After a trade-name drug's patent expires, how may generic versions of it be sold?
A. only under the branded generic name
B. only under the generic name
C. only under the original trade name
D. under the original trade name or a generic name
132. What is required for a new pharmaceutical to be considered a viable therapy?
133. Under the AMA guidelines, who is ultimately responsible for minimizing conflicts of interest?
B. lawyers and office managers
C. pharmaceutical companies
D. sales representatives
134. The act of dispensing a pharmaceutical alternative for the product prescribed is
A. alternative licensure
B. equivalence practice
C. necessitated substitution
D. pharmaceutical substitution
135. What does it mean if a drug is said to have a wide margin of safety?
136. Which of the following is the correct medical acronym for effective dose?
D. eff D
137. Why is one group of subjects given an active drug, while another group only receives a placebo?
A. to assess patients' expectations
B. to assess the drug's effectiveness
C. to assess the professionalism of the study staff
D. to assess the subjects' demographics
139. Which of the following is an example of a functional value?
140. Where are most drugs metabolized?
A. interstitial spaces
D . the bloodstream
141. What is essential to the ethical requirement that subjects be selected fairly?
D. all of these
142. Which of the following is the most appropriate salutation for a cover letter if you cannot find a contact name?
B. Dear Sir or Madam,
C. Dear Sir
143. What is part of becoming an indispensable pharmaceutical sales rep?
A. asking for feedback
B. giving the doctors anything they ask for to prescribe your products
C. keeping your market share goals the same each term
D. not bothering busy doctors in hospitals
144. Which of the following is NOT typically included in the indications and usage section of the package insert information?
A. diseases or conditions that the drug is approved to treat
B. the drug's active metabolites
C. the drug's recommended usual dosage
D. the drug's usual dosage range
145. Which term denotes the practice of classifying physicians and other potential prescribers by anticipated prescription volume?
D. private labeling
146. What makes a drug eligible for fast track approval from the FDA?
C. dispersing agents
148. According to your manual, what does the PDRP do?
149. What are the components of the central nervous system?
A. the brain and sense organs
B. the brain and spinal cord
D. the spinal cord and sense organs
150. Which term denotes the origin or cause of a medical condition?
152. Which DTC pharmaceutical marketing tactic is permitted in European countries?
A. disease state ads
B. branded billboards and disease state ads
C. branded highway billboards
D. branded radio ads
153. What is one way in which psychologists DIFFER from psychiatrists?
154. What are PBMs?
A. governmental organizations that provide healthcare
B. organizations that design marketing campaigns
C. organizations that negotiate between pharmaceutical companies and large drug purchasers
D. organizations that write FDA new drug applications
155. How does the Hatch-Waxman Act protect research-based drug manufacturers?
A. by limiting the competition
B. by making it easier to bring generic drugs to market
C. by providing a 30-month cooling off period
D. by requiring the FDA to only look at bioavailability studies when approving an ANDA
156. What is the process of adjusting drug doses to achieve the maximum positive therapeutic effects while minimizing adverse or side effects?
A. homeostatic maximization
B. steady stateadministration
157. Which of the following is studied more in pharmacodynamics than in pharmacokinetics?
B. dose-response effects
C. the transportation of the drug to the specific site for drug-receptor interaction
D. the way the human body deals with a drug after it has been administered
158. How does the healthy human immune system use MHC markers?
159. What is a behind-the-counter drug?
A. an OTC drug that must be closely monitored by the pharmacist
B. another term for a generic prescription drug
C. another term for a prescription drug
D. another term for an OTC drug
160. When do MSLs meet with clinicians?
A. at nearly any stage of the product's life cycle
B. only after the district's sales representatives
C. only prior to launch